The Health Fact

What is Valproic Acid Side Effects and Who can use it

Valproic Acid Side Effects

Valproic acid is an anti-epileptic utilized to treat a variety of seizure disorders but sometimes valproic acid side effects are also seen. Valproic acid is sometimes used with other seizure medications. Valproic acid is available under the following different brand names: Depakene, Stavzor, ​​and Depacon.

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Valproic Acid Side Effects

With valproic acid needed effects, this medicine may cause some unwanted valproic acid side effects. While not all of these side effects may occur, they may require medical attention if they do occur.

Consult with your doctor immediately if any of the following side effects occur-

Some Valproic acid side effects that require immediate medical attention-

More common immediate medical attention from Valproic acid side effects is-

Less common immediate medical attention from Valproic acid side effects is-

Incidence not known of immediate medical attention from Some Valproic acid side effects is-

Some Valproic acid side effects that not require immediate medical attention

Some sort of side effects of valproic acid may occur which usually don’t need medical attention. In addition with these side effects may go away during treatment because your body adjusts to the medicine. Also, your health care professional can be able to tell you about various ways to prevent or reduce some of these side effects.

Check and consult with your health care professional if any of these following side effects continue or are irritates you or if you may have any questions about them-

More common Some Valproic acid side effects that do not require immediate medical attention

Less common Some Valproic acid side effects that do not require immediate medical attention-

Incidence not known some Valproic acid side effects that not require immediate medical attention-

Why is Valproic Acid medication prescribed?

Valproic acid usually is used alone or with other medications to cure specific types of seizures. Valproic acid is also utilized to treat mania (episodes of manic, unusually agitated mood) in individuals with bipolar disorder (manic-depressive disorder; an illness characterized by episodes of depression, episodes of mania, and another sort of abnormal moods).

This may also be used to prevent migraine headaches but not to relieve and relax headaches that have already started. Valproic acid is in a class of medications called anticonvulsants. It mainly works by increasing the amount of a certain natural substance in your brain.

Valproic Acid Key Facts to Remember Before use

  1. It is common to take valproic acid 2 or 3 times a day. You can even take it with or without food.
  2. If you are pregnant or there is a chance that you will become pregnant, valproic acid is not recommended for bipolar disorder or migraine. For epilepsy, your doctor will only prescribe valproic acid for you if there are no other suitable treatments.
  3. You will usually start on a low dose. Your dose will be increased gradually over a few days or weeks.
  4. Sodium valproate and semisodium valproate are the same as valproic acid and work in the same way. However, these drugs are used to treat different diseases and the dosage will vary.
  5. There are also brands such as Epilim Chrono and Epilim Chronosphere that contain mostly sodium valproate with some valproic acid.

Valproic Acid Side Effects Symptoms of Overdose 

Get immediate emergency help immediately if any of the following symptoms of overdose occur while taking valproic acid

FAQ’s Related to Valproic Acid Side Effects

What are the adverse effects of valproic acid?

Diarrhea, dizziness, drowsiness, hair loss, blurred/double vision, changes in menstrual periods, ringing in the ears, tremors (tremors), unsteadiness, weight changes may occur. If you face any of these effects or some other effects and which may suddenly worsen, tell your doctor or pharmacist urgently.

What does valproic acid do to the brain?

How does valproic acid affect the brain? Brain cells need to work (fire) at a certain rate to function normally. During seizures, brain cells are forced to work faster than normal. Valproic acid helps prevent brain cells from working as fast as are needed for seizures.

Valproic acid vs Depakote?

Depakote (divalproex sodium) is a stable coordination compound consisting of sodium valproate and valproic acid that is used to treat manic episodes associated with bipolar disorder, epilepsy, and migraine headaches. The generic Depakote (called divalproex sodium) is available under several other names.

What do you watch for while taking valproic acid?

Obtain baseline complete blood cell count with differential (with CBC difference); Liver function test and pregnancy test for women. Monitor Depakote levels, liver function tests, and CBC every 3-6 months. Monitor the development of polycystic ovary disease in women.

What are the serious side effects of Depakote?

Diarrhea, dizziness, drowsiness, hair loss, blurred/double vision, changes in menstrual periods, ringing in the ears, tremors (tremors), unsteadiness, weight changes may occur. If you face any of these effects or some other effects and which may suddenly worsen, tell your doctor or pharmacist urgently. You may rarely see fractional tablets in your stool.

Another name of Valproic acid is Depakote?

Valproic acid other names are-  Depakote, Convulex, Syonell, Belvo.

Did valproic acid damage the brain?

Valproic acid can cause major birth defects (physical problems present at birth), especially affecting the brain and spinal cord, and may cause low intelligence and problems with movement and coordination, learning, communication, emotions, and behavior of babies who have been exposed to valproic acid before birth which may create a further problem.

Is Valproic Acid Safe?

It is uncommon for serious side effects to occur after taking valproic acid. Tell the doctor right away if you have: thoughts of harming or killing yourself – a small number of people taking valproic acid have suicidal thoughts. Yellowing of your skin or the whites of your eyes – these can be warning signs of liver problems.

Why does valproic acid cause weight gain?

Changes in energy intake or expenditure may result from, or be associated with, changes in biological mechanisms, including hormone levels. In vitro studies tells that VPA initiates pancreatic insulin secretion which may increase appetite and energy storage and which then result in weight gain.

Can Valproic Acid Cause Depression?

Valproic acid can cause some people to become agitated, irritable, or exhibit other unusual behavior. This can cause suicidal thoughts and tendencies in some people or make them more depressed.

Can you stop taking valproic acid?

Do not stop using valproic acid suddenly, even if you feel well. Stopping suddenly can cause a serious, life-threatening type of seizure. Follow your doctor’s instructions about reducing your dose.

Can you drink alcohol while taking valproic acid?

Valproic acid capsules may cause drowsiness and dizziness. So do not drink alcohol or take other types of medicines that make you sleepy or dizzy while taking valproic acid capsules, unless you consult with your doctor.

How do you reduce sodium valproate?

Medications such as phenytoin and valproate can be tapered to zero in a few days, carbamazepine, lamotrigine, and vigabatrin over 2-3 weeks, and clonazepam, clobazam, and primidone over weeks to months.

Did Valproic Acid help Depression?

Valproic acid may be specifically helpful for patients who have symptoms and signs of mania and depression at the same time (a ‘mixed’ episode) or who have more than four mood episodes per year (this is called ‘rapid cycling’). This drug can also particularly target aggressive or impulsive behavioral problems.

 

 

 

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